Brain Network Organization and Social Executive Performance in Frontotemporal Dementia
نویسندگان
چکیده
منابع مشابه
Brain Network Organization and Social Executive Performance in Frontotemporal Dementia.
OBJECTIVES Behavioral variant frontotemporal dementia (bvFTD) is characterized by early atrophy in the frontotemporoinsular regions. These regions overlap with networks that are engaged in social cognition-executive functions, two hallmarks deficits of bvFTD. We examine (i) whether Network Centrality (a graph theory metric that measures how important a node is in a brain network) in the frontot...
متن کاملIntelligence and executive functions in frontotemporal dementia
Recently (Roca et al. (2010), we used the relationship with general intelligence (Spearman's g) to define two sets of frontal lobe or "executive" tests. For one group, including Wisconsin card sorting and verbal fluency, reduction in g entirely explained the deficits found in frontal patients. For another group, including tests of social cognition and multitasking, frontal deficits remained eve...
متن کاملExecutive functions in frontotemporal dementia and Lewy body dementia.
Diagnosis of different types of dementia is often based on clinical symptomatology rather than underlying pathology; therefore, accurate diagnosis depends on a thorough description of cognitive functioning in different dementias. Furthermore, direct comparison of cognitive functions between different types of dementia is necessary for differential diagnosis. Executive dysfunction is common in s...
متن کاملExecutive function in progressive and nonprogressive behavioral variant frontotemporal dementia.
BACKGROUND Recent studies suggest that behavioral variant frontotemporal dementia (bv-FTD) patients differ in their prognosis with fast-progressing and very slow-progressing cases. We investigated executive and behavioral profiles of progressive and nonprogressive bv-FTD patients to establish diagnostic markers discriminating the two groups. METHODS A range of neuropsychological and behaviora...
متن کاملImpulsivity, decreased social exploration, and executive dysfunction in a mouse model of frontotemporal dementia.
Frontotemporal lobar degeneration (FTLD) is a neurodegenerative disorder, a major subset of which is characterized by the accumulation of abnormal forms of the protein tau, leading to impairments in motor functions as well as language and behavioral alterations. Tau58-2/B mice express human tau with the P301S mutation found in familial forms of FTLD in neurons. By assessing three age cohorts of...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the International Neuropsychological Society
سال: 2016
ISSN: 1355-6177,1469-7661
DOI: 10.1017/s1355617715000703